Difficult biliary stones in the elderly: Endoscopic retrograde cholangiography – A single surgical tertiary centre experience with follow-up Antypas P, Cereatti F, Fiocca F, Cappello A, Eberspacher C, Fanello G, Mascagni D, Donatelli G,

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Difficult biliary stones in the elderly: Endoscopic retrograde cholangiography – A single surgical tertiary centre experience with follow-up Pavlos Antypas¹, Fabrizio Cereatti², Fausto Fiocca³, Annalisa Cappello³, Chiara Eberspacher⁴, Gianfranco Fanello³, Domenico Mascagni⁴, Gianfranco Donatelli⁵ ¹ Department of Emergency, Endoscopy Unit, Policlinico Umberto I Sapienza University of Rome; Department of Surgical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy ² Department of Medical, Gastroenterology and Endoscopy Unit, ASST Cremona, Cremona, Italy ³ Department of Emergency, Endoscopy Unit, Policlinico Umberto I Sapienza University of Rome, Rome, Italy ⁴ Department of Surgical Sciences, Policlinico Umberto I, Sapienza University of Rome, Rome, Italy ⁵ Interventional Endoscopy Unit, Private Hospital Des Peupliers-Ramsay Santé, Paris, France Correspondence Address: Gianfranco Donatelli, Interventional Endoscopy Unit, Private Hospital Des Peupliers-Ramsay Santé, 8 Place De L'abbè G. Henocque, 75013, Paris France Source of Support: None, Conflict of Interest: None DOI: 10.4103/jmas.JMAS_162_20

Background: Pancreaticobiliary diseases and choledocholithiasis are common in elderly patients. Endoscopic treatment of biliary stones represents a well-established mini-invasive technique. However, limited data are available regarding the treatment of 'difficult' biliary stones, especially in the elderly population. The aim of our study is to evaluate the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) in patients ≥85 years of age with complex biliary stones. Materials and Methods: From January 2015 to January 2017, data from ERCP procedures performed for complex biliary stones were retrospectively collected. The patients were divided into two groups based on their age: Group A – aged 85 years or older (n = 110) and Group B – aged 65 years or younger (n = 62). Demographic data, success, complications and recurrence rates for both groups were reported. Results: Chronic comorbidities (86.3% vs. 24.2%; P < 0.001) and use of antithrombotic drugs (48.2% vs. 19.3%; P < 0.001) were more frequent in the elderly. The technical success rate (95.4% vs. 96.7%; P > 0.6) and complication rate (8.2% vs. 13%; P > 0.2) were not statistically different among the two groups. Periampullary diverticula (PAD) were observed more frequently in Group A (38.1% vs. 17.7%; P < 0.006). More patients from Group B underwent cholecystectomy during the same admission (8.2% vs. 42.3%; P < 0.001). The recurrence rate was not different among the groups (7.6% vs. 5%; P > 0.5). PAD was identified as the risk factor for recurrence (P < 0.02). Conclusion: ERCP in the elderly was found to be a safe procedure, carrying a high degree of success for the treatment of difficult biliary stones.

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    -  Antypas P
    -  Cereatti F
    -  Fiocca F
    -  Cappello A
    -  Eberspacher C
    -  Fanello G
    -  Mascagni D
    -  Donatelli G

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