| ORIGINAL ARTICLE
|Year : 2021 | Volume
| Issue : 2 | Page : 159-164
Is weight regaining significant post laparoscopic Roux-en-Y gastric bypass surgery? – A 5-year follow-up study on Indian patients
Mohamed Ismail1, Dileep Nagaraj1, Mahesh Rajagopal1, Hafiz Ansari1, Kingsly Iyyankutty1, Megha Nair2, Aparna Hegde2, PD Rekha2
1 Department of General, Laparoscopic and Bariatric Surgery, Moulana Hospital, Perinthalmanna, Kerala, India
2 Yenepoya Research Centre, Yenepoya University, Mangalore, Karnataka, India
Background: Laparoscopic Roux-en-Y gastric bypass (RYGB) has been proven to induce significant weight loss and remission of related co-morbidities in patients with morbid obesity. The long-term follow-up data show weight regain or failure to achieve complete remission of type 2 diabetes mellitus (T2DM) in some patients. In this study, we report weight loss patterns and remission of T2DM in patients with morbid obesity during a 5-year follow-up after RYGB.
Objective: The objective was to evaluate outcomes during the follow-up on excess weight loss (EWL) and remission of T2DM after laparoscopic RYGB among Indian patients.
Setting: The study was conducted in a tertiary care hospital, Kerala, India.
Materials and Methods: This is a retrospective study in patients who underwent surgery between 2007 and 2010. The patient demographics, pre- and post-operative body mass index (BMI), co-morbidities and EWL were recorded from the medical records. These data were compared between pre-operative and follow-up intervals till 5 years using statistical approaches.
Results: The study included 157 patients (91 males and 66 females) having a mean pre-operative BMI of 47.91 ± 7.01 kg/m2. A significant reduction in the BMI was observed at each follow-up point (P < 0.01) till 5 years after the surgery. The mean percentage of EWL increased from 34.57% ± 12.62% to 71.50% ± 15.41% from 3 months to 5 years after the surgery. Twelve per cent (n = 19) of patients achieved normal BMI (<25 mg/kg2) by 3rd year after the surgery. However, the remission of T2DM was achieved in >50% of patients within a year of surgery. During the 5th year, weight regain (1–22 kg) was observed in 36.70% (n = 58) patients, and recurrence of T2DM was observed in two patients.
Conclusions: The long-term durability of RYGB in the study population was satisfactory with significant weight loss and remission of T2DM.
Dr. Mohamed Ismail
Department of General, Laparoscopic and Bariatric Surgery, Moulana Hospital, Perinthalmanna, Kerala
Source of Support: None, Conflict of Interest: None
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