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ORIGINAL ARTICLE
Ahead of Print

End-stage renal disease is a risk factor for complex laparoscopic cholecystectomy in patients waiting for renal transplantation


 Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy

Correspondence Address:
Samuele Iesari,
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Via Pompeo Spennati, 67100 L'Aquila
Italy
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmas.JMAS_145_17

PMID: 29483371

Introduction: To date, there are no studies investigating whether laparoscopic cholecystectomy (LC) is technically more complex in patients waiting for kidney transplant. The aim of this study is to create a user-friendly score to identify high-risk cases for complex LC integrating end-stage renal disease (ESRD). Materials and Methods: We retrospectively analysed 321 patients undergoing LC during the period 2014–2016. Two groups were compared: ESRD group (n = 25) versus control group (n = 296). Concerning statistical analysis, continuous variables were compared using Kruskal–Wallis' test, dummy variables with Chi-square test or Fisher's exact test when appropriate. A multivariable logistic regression analysis was performed to identify risk factors for complex LC. A backward conditional method was used to design the final model. Results: Seventy out of 321 (21.8%) cases were considered as complex, with a higher prevalence in the ESRD group (32.0 vs. 20.9%; P = 0.2). Using a multivariable logistic regression analysis, we formulated a score based on the independent risk factors for complex LC: 4×(previous cholecystitis) +5 × (previous ESRD) +1 × (age per decade) +2 × (previous open abdominal surgery). High-risk cases (score ≥ 10) were more commonly reported in the ESRD group (72.0 vs. 24.7%; P < 0.0001). Conclusion: Although several scores investigating the risk for complex LC have been proposed, none of them has focused on ESRD. This is the first series demonstrating that ESRD is an independent risk factor for technical complexity in LC. We developed a score to offer surgeons an extra tool for pre-operative evaluation of patients requiring LC.


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    -  Colozzi S
    -  Iesari S
    -  Cianca G
    -  Lai Q
    -  Bonanni L
    -  Pisani F
    -  Amicucci G
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2004 Journal of Minimal Access Surgery
Published by Wolters Kluwer - Medknow
Online since 15th August '04