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| ORIGINAL ARTICLE
|Year : 2018 | Volume
| Issue : 4 | Page : 277-284
Surgical outcome of laparoscopic hepatic resection for hepatocellular carcinoma: A matched case–control study with propensity score matching
Tsutomu Iwata1, Kenta Murotani2, Shunichiro Komatsu1, Hideyuki Mishima2, Takashi Arikawa1
1 Department of Gastroenterological Surgery, Aichi Medical University School of Medicine, Aichi, Japan
2 Department of Center for Clinical Research, Aichi Medical University School of Medicine, Aichi, Japan
Background: Although the number of reports on laparoscopic hepatic resection (LHR) has increased, studies of long-term outcomes regarding tumor recurrence and patient survival compared to the conventional open approach are limited. We evaluated the long-term survival and feasibility of LHR in patients with hepatocellular carcinoma (HCC).
Patients and Methods: A retrospective analysis was performed on the clinical data of patients who underwent hepatic resection for primary HCC between August 2000 and December 2013. The patients were divided into the LHR or open hepatic resection (OHR) groups. To control for selection bias in the two groups, propensity score matching was used at a 1:1 ratio based on the following covariates: Child–Pugh grade, tumour size, tumour number and tumour location. Following propensity score matching, thirty patients were included in the LHR group and thirty were included in the OHR group.
Results: The respective disease-free survival rates at 1 year, 3 years and 5 years were 78.4%, 61.1% and 38.9%, respectively, for the LHR group, and 89.3%, 57.5% and 47.9%, respectively, for the OHR group (P = 0.89). Also, the overall survival rates at 1 year, 3 years and 5 years were 96.4%, 68.2% and 62.5%, respectively, for the LHR group and 100.0%, 95.8% and 72.3%, respectively, for the OHR group (P = 0.44).
Conclusions: According to our study, using propensity score matching, LHR for HCC is safe, feasible and comparative, with good oncologic results.
Dr. Takashi Arikawa
Department of Gastroenterological Surgery, Aichi Medical University, School of Medicine, 1-1 Yazako-Karimata, Nagakute, Aichi 480-1195
Source of Support: None, Conflict of Interest: None
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