|Year : 2012 | Volume
| Issue : 4 | Page : 152-153
Two-stage laparoscopic resection of colon cancer and metastatic liver tumour
Yukio Iwashita, Atsushi Sasaki, Toshifumi Matsumoto, Kohei Shibata, Masafumi Inomata, Masayuki Ohta, Seigo Kitano
Department of Surgery I, Oita University Faculty of Medicine, Oita, Japan
|Date of Submission||24-Jan-2005|
|Date of Acceptance||05-Mar-2005|
|Date of Web Publication||2-Nov-2012|
Department of Surgery I, Oita University Faculty of Medicine, 1-1 Hasama-machi, Oita
Source of Support: None, Conflict of Interest: None
We report herein the case of 70-year-old woman in whom colon cancer and a synchronous metastatic liver tumour were successfully resected laparoscopically. The tumours were treated in two stages. Both post-operative courses were uneventful, and there has been no recurrence during the 8 months since the second procedure.
Keywords: Colorectal cancer, laparoscopic hepatectomy, laparoscopy-assisted colectomy, metastatic liver tumor, two-stage procedure
|How to cite this article:|
Iwashita Y, Sasaki A, Matsumoto T, Shibata K, Inomata M, Ohta M, Kitano S. Two-stage laparoscopic resection of colon cancer and metastatic liver tumour. J Min Access Surg 2012;8:152-3
|How to cite this URL:|
Iwashita Y, Sasaki A, Matsumoto T, Shibata K, Inomata M, Ohta M, Kitano S. Two-stage laparoscopic resection of colon cancer and metastatic liver tumour. J Min Access Surg [serial online] 2012 [cited 2020 Jul 13];8:152-3. Available from: http://www.journalofmas.com/text.asp?2012/8/4/152/103128
| ¤ Introduction|| |
Laparoscopy is used as minimal access surgery for colorectal cancer and liver tumours.  Herein, we describe a case of colon cancer and synchronous liver metastasis in which both tumours were treated laparoscopically.
| ¤ Case Report|| |
A 70-year-old woman was admitted to our hospital with a diagnosis of cancer of the sigmoid colon. Barium enema showed an encircling mass in the sigmoid colon [Figure 1]. Computed tomography (CT) revealed a low-density area in the left lateral segment of the liver [Figure 2]. Liver function was normal, and the pre-operative carcinoembryonic antigen level was 6.2 ng/ml (normal range, < 5 ng/ml). The patient had no history of abdominal surgery. We planned two-stage procedure for the patient because it was considered to be a highly invasive treatment for this elder patient when both sigmoid colectomy and hepatectomy were performed simultaneously. In addition, interval hepatic resection for synchronous metastases of colorectal cancer, with a routine waiting period of 4-6 months, was recommended to improve the patient selection.  Therefore, laparoscopic sigmoid colectomy was performed first. With the patient in the supine position, pneumoperitoneum of 8 mmHg was established, and trocars were placed in the right upper and lower abdomen [Figure 1]. After the sigmoid colon was mobilised from the surrounding tissues, a skin incision (6 cm) was made in the left lower abdomen. The sigmoid colon was exteriorised and resected through the skin incision after appropriate barrier protection of the wound edges was ensured. Operation time was 372 min, and estimated blood loss was 70 ml. The post-operative course was uneventful, first flatus was recognised on day 2, solid diet was started on day 3, the patient was discharged and directly went home on post-operative day 11.
|Figure 1: (a) Barium enema shows an encircling tumuor in the sigmoid colon (arrows) (b) Port sites for laparoscopy assisted sigmoid colectomy|
Click here to view
|Figure 2: (a) Computed tomographic scan shows a metastatic liver tumour (arrow) (b) Port sites for laparoscopic partial hepatectomy|
Click here to view
Five months after the first operation, CT scan revealed that the slight enlargement of the liver tumour (25-37 mm in diameter), but new lesions were not observed [Figure 2]. We performed laparoscopic partial S2/3 hepatectomy. After CO 2 insufflation with a pressure of 8 mmHg, inspection of the peritoneal cavity revealed no remarkable adhesion. Four trocars were placed in the upper abdomen, as shown in [Figure 2]. The falciform, left triangular and coronary ligaments were dissected, and the left hepatic lobe was mobilised. Hepatic resection was performed with an endoscopic autosuture stapler (EndoGIAII, US Surgical, Norwalk, CT, USA) under lower pneumoperitoneum pressure to prevent gas embolism. The resected specimen was removed from the port site, which was enlarged to 3 cm in the supraumbilical area with an EndoCatchII device (US Surgical). Operation time was 167 min, and blood loss was 20 ml. The post-operative course was uneventful and the patient was discharged and directly went home on day 14. She is currently doing well, with no evidence of disease recurrence during the 8 months since the procedure.
| ¤ Discussion|| |
Laparoscopic surgery has become a standard technique for the treatment of benign diseases. Further development of instruments and techniques has made it possible to apply laparoscopic surgery to malignant diseases.  To our knowledge, this is the first report of laparoscopic resection of both primary tumour and metastatic liver tumour. In comparison to conventional surgery, laparoscopic surgery is beneficial with respect to short-term outcome, including earlier recovery and less pain. Our research in a murine model has shown that laparoscopic surgery is advantageous for gastrointestinal malignancies due to reduced impairment of systemic and intraperitoneal cell-mediated immune responses.  Although a comparison of long-term outcomes between laparoscopic and conventional surgeries for advanced colon cancer has been recently published,  there have been no reports of randomised trials of laparoscopic hepatectomy in patients with metastatic liver tumours. Future study is needed to further evaluate the usefulness of laparoscopic hepatectomy.
| ¤ References|| |
|1.||O'Rourke N, Fielding G. Laparoscopic right hepatectomy: Surgical technique. J Gastrointest Surg 2004;8:213-6. |
|2.||Lambert LA, Colacchio TA, Barth RJ Jr. Interval hepatic resection of colorectal metastases improves patient selection. Arch Surg 2000;135:473-9;discussion 9-80. |
|3.||Kitano S, Shiraishi N, Fujii K, Yasuda K, Inomata M, Adachi Y. A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: An interim report. Surgery 2002;131:S306-11. |
|4.||Fujii K, Izumi K, Sonoda K, Shiraishi N, Adachi Y, Kitano S. Less impaired cell-mediated immune response in the murine peritoneal cavity after CO(2) pneumoperitoneum. Surg Today 2003;33:833-8. |
|5.||Clinical Outcomes of Surgical Therapy Study Group. A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 2004;350:2050-9. |
[Figure 1], [Figure 2]